0121 - Apoptosis in Pseudomembranes of Aseptically Loose Total Hip Arthroplasty: Implication of a Caspase-3-dependent, P53 Independent Pathway
نویسنده
چکیده
Relevance to Musculoskeletal Conditions The identification of apoptosis in pseudomembranes (PMs) of aseptically loose Total Hip Arthroplasty (THA) may offer specific target points for therapeutic modulation of osteolysis. The identification of a specific pathway leading to apoptosis contributes to our understanding of the mechanism leading to periprosthetic osteolysis and to a more rational strategy for the treatment and/or prevention of osteolysis.
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